COVID-19 V.S.Houttuynia Cordata

COVID-19 V.S.Houttuynia Cordata. This report are research and analysis which summary by NSPi from THAILAND.(click see more detail)

COVID-19 V.S. Houttuynia Cordata

Houttuynia cordata and Coronaviruses

Coronaviruses (CoVs) is a large family of enveloped single-stranded RNA viruses, which can infect a wide variety of animals, including humans. They are the cause of many respiratory, enteric, hepatic and neurological diseases, including the Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).1,2 As the largest known RNA viruses, CoVs are further divided into four genera: alpha-, beta-, gamma- and delta-coronavirus.2 Both SARS-CoV and MERS-CoV are characterised as betacoronaviruses. Both are zoonotic in origin, with the SARS epidemic originating from an animal market in South China and MERS-CoV infection occurring through direct or indirect contact with infected dromedary camels.6, 7

Severe acute respiratory syndrome (SARS) is a life-threatening form of pneumonia caused by SARS coronavirus (SARS-CoV). From late 2002 to mid 2003, more than 8000 people were infected worldwide, with 916 deaths in 29 countries.2

COVID-19  V.S. Houttuynia Cordata

The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe pneumonia with multiorgan involvement (including acute renal failure).4  Between 2012 – 2017, 2066 cases of MERS-CoV infection have been reported in 27 countries, with at least 720 deaths. More that 80% of illnesses were reported from Saudi Arabia.2,4

Although human-to-human transmission was not self-sustaining in the case of MERS-CoV, transmission in healthcare settings with inadequate infection control precautions were prominent features of both SARS and MERS; 19% to 57% of probable SARS cases worldwide were amongst healthcare workers and hospitalised patients and 43.5–100% of MERS patients in individual outbreaks were linked to hospitals.2,5,6,7

COVID-19  V.S. Houttuynia Cordata

Transmission of SARS-CoV is primarily from person to person, with viral particles found in respiratory secretions, faeces and urines of infected individuals.5 The transmission route is mainly through respiratory droplets and direct contact, although the role of indirect contact transmission (through contaminated surfaces) have been implicated.8


Houttuynia cordata Thunb. is a member of Saururaceae, a family mainly distributed in Eastern Asia. It has long been used in China both as an edible vegetable and in traditional medicine.3 During the 2003 SARS outbreak, the Chinese government set up the Science and Technology Group of the National Headquarters for SARS Prevention and Control and scientists were encouraged to investigate and utilize traditional herbal medicines as potential drugs. H. cordata became one of the candidates for treating SARS in China.3

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COVID-19 V.S.Houttuynia Cordata.

COVID-19  V.S. Houttuynia Cordata

Houttuynia cordata extract has been shown to exhibited significant inhibitory

effects on SARS-CoV 3C-like protease (3CLpro) and RNA-dependent RNA polymerase (RdRp) in vitro.9 It has also been shown to inhibit viral infectivity of the murine coronavirus, mouse hepatitis virus (MHV), for up to 6 days.4 Active compounds found in H. cordata extracts were able to affect the initial stage of Porcine epidemic diarrhea virus (PEDV) infection by interfering with its viral mRNA production and were able to protect cells from PEDV induced cell-death. 10,11

COVID-19 in THAILAND  we have reported for proved that patients with infection coronaviruses after taking “VILERTONG”  after 72 hours shown as significant improvment in symptoms.Coronaviruses has been killed by Houttuynia cordata extract.So that Thai people there for safe from crisis COVID-19 forever.

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  1. Weiss, R., & Leibowitz, J. L. (2011). Coronavirus pathogenesis. Advances in virus research, 81, 85–164. DOI: 10.1016/B978-0-12-385885-6.00009-2
  2. Yin Y, Wunderink MERS, SARS and other coronaviruses as causes of pneumonia. (2018)

Respirology. 23(2):130–137. DOI: 10.1111/resp.13196

  1. Yang & Jiang J. G. (2009) Bioactive components and functional properties of Hottuynia cordata and its applications, Pharmaceutical Biology, 47:12, 1154-1161,

DOI: 10.3109/13880200903019200

  1. Chiow H., Phoon M.C., Putti T., Tan B. K.H., Chow V. T. (2016) Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection, Asian Pacific Journal of Tropical Medicine, 9:1, 1-7, DOI: 10.1016/j.apjtm.2015.12.002.
  2. Lee, , & Sung, J. J. (2003). Nosocomial Transmission of SARS. Current infectious disease reports, 5(6), 473–476.
  3. Cauchemez S, Nouvellet P, Cori A, et (2016) Unraveling the drivers of MERS-CoV transmission. Proc Natl Acad Sci USA. 113(32):9081–9086. doi:10.1073/pnas.1519235113
  4. de Wit, , van Doremalen, N., Falzarano, D., & Munster, V. J. (2016). SARS and MERS: recent insights into emerging coronaviruses. Nature reviews. Microbiology, 14(8), 523– 534.
  5. Otter, A., Donskey, C., Yezli, S., Douthwaite, S., Goldenberg, S. D., & Weber, D. J. (2016). Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination. The Journal of hospital infection, 92(3), 235–250.
  6. Lau, -M., Lee, K.-M., Koon, C.-M., Cheung, C. S.-F., Lau, C.-P., Ho, H.-M., … Fung, K.-P. (2008). Immunomodulatory and anti-SARS activities of Houttuynia cordata. Journal of Ethnopharmacology, 118(1), 79–85. DOI: 10.1016/j.jep.2008.03.018
  7. Choi, J., Kim, J. H., Lee, C. H., Ahn, Y. J., Song, J. H., Baek, S. H., & Kwon, D. H. (2009). Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus. Antiviral research, 81(1), 77–81.
  8. Song, H., Shim, J. K., & Choi, H. J. (2011). Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species. Virology journal, 8, 460. DOI: 10.1186/1743-422X-8-460